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目的探讨个性化护理对应用非典型抗精神病药物导致便秘的干预作用。方法选取杭州市第七人民医院2014年7月—2016年5月符合纳入标准的因服用氯氮平导致便秘患者86例,按随机数字表法分为对照组和研究组,分别为43例,对照组予以常规护理;研究组予以个性化护理,2组共干预3个月为一疗程,治疗期间评定Longo出口梗阻评分、Wexner便秘严重度评分、胃肠生活质量评分以及焦虑自评量表(SAS)、抑郁自评量表(SDS)、简明健康调查问卷(SF-36)等,同时对比2组间护理效果以及满意度状况。结果与治疗前比较,2组治疗后Longo出口梗阻评分、Wexner便秘严重度评分降低,胃肠生活质量评分升高,治疗后SAS、SDS评分降低,SF-36评分升高(P<0.05);与对照组比较,研究组治疗后Longo出口梗阻评分、Wexner便秘严重度评分较低,胃肠生活质量评分较高,治疗后SAS、SDS评分较低,SF-36评分较高(P<0.05);研究组有效率(90.70%)高于对照组(72.09%),P<0.05;研究组满意率(88.37%)高于对照组(65.12%),P<0.05;所有患者均进行随访,无病例脱落现象,治疗期间肝/肾、血/尿、离子检测均处于正常范围,2组患者无不良反应出现。结论个性化护理对氯氮平所致的便秘疗效确切,可以改善便秘症状,提高生存质量,值得推广。
Objective To explore the effect of personalized nursing intervention on atypical antipsychotics induced constipation. Methods Seventh People’s Hospital of Hangzhou from July 2014 to May 2016 in line with inclusion criteria for taking clozapine 86 cases of constipation patients were divided into control group and study group according to random number table method were 43 cases, The control group was given routine nursing care. The study group was given personalized care. The two groups were treated for a total of three months as a course of treatment. Longo outlet obstruction score, Wexner constipation severity score, gastrointestinal quality of life score and anxiety scale SAS, SDS, SF-36 and so on. At the same time, the nursing effect and the satisfaction status between the two groups were compared. Results Compared with those before treatment, Longo outlet obstruction score, Wexner constipation severity score and gastrointestinal quality of life score increased. After treatment, the scores of SAS and SDS decreased and SF-36 score increased (P <0.05). Compared with the control group, Longo outlet obstruction score, Wexner constipation severity score, gastrointestinal quality of life score were higher in the study group after treatment, the score of SAS and SDS was lower and SF-36 score was higher (P <0.05) (90.70%) was higher than that of the control group (72.09%), P <0.05; The satisfaction rate of the study group was 88.37%, which was higher than that of the control group (65.12%), P <0.05. All the patients were followed up Case shedding phenomenon, liver / kidney, blood / urine, ion detection were in the normal range during the treatment, two groups of patients without adverse reactions. Conclusion Individualized nursing is effective in treating constipation caused by clozapine, which can improve the symptoms of constipation and improve the quality of life, which deserves promotion.