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巨幼细胞贫血是多种原因引起的以增殖细胞呈巨幼变为形态特征的一组贫血综合征,DNA合成速度减慢是其共同的生化基础。当体内储存的叶酸或维生素B_(12)耗竭不能满足机体造血需要时,出现营养性巨幼细胞贫血,它是叶酸和维生素B_(12)缺乏的晚期表现。据统计巨幼细胞贫血病因中,95％为营养性叶酸或维生素B_(12)缺乏。诊断营养性巨幼细胞贫血,叶酸或维生素B_(12)治疗必须有特效。
Megaloblastic anemia is a group of anemia syndrome characterized by proliferative cells that have proliferated into giant cells due to a variety of causes. The slow pace of DNA synthesis is a common biochemical basis. Nutritional megaloblastic anemia occurs when in vivo stored folic acid or vitamin B 12 depletion fails to meet the body’s hematopoietic needs and is a late manifestation of folic acid and vitamin B 12 deficiency. According to the statistics of megaloblastic anemia, 95% of the nutritional folic acid or vitamin B_ (12) deficiency. Diagnosis of megaloblastic anemia, folic acid or vitamin B_ (12) treatment must have special effects.