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目的研究连续性肾脏替代治疗(cotinuous renal replacement therapy,CRRT)在难治性心肾综合征的治疗中的重要作用。方法观察患者治疗前后的症状、体征,监测血气、末梢血氧饱和度、血肌酐、尿素氮、胱抑素C、左心室射血分数、BNP等指标比较分析。结果难治性心肾综合征患者经CRRT后动脉血氧分压、末梢血氧饱和度升高;血肌酐、尿素氮、胱抑素C、BNP下降;左心室射血分数增高,指标间差异有统计学意义(P<0.05)。结论 CRRT在难治性心肾综合征治疗中的起着重要作用,能改善心肾功能,提高生存质量。
Objective To study the important role of cotinuous renal replacement therapy (CRRT) in the treatment of refractory cardiorenal syndrome. Methods The symptoms, signs, blood gas, peripheral blood oxygen saturation, serum creatinine, blood urea nitrogen, cystatin C, left ventricular ejection fraction and BNP were compared before and after treatment. Results In patients with refractory cardiorenal syndrome, arterial oxygen pressure and peripheral oxygen saturation increased after CRRT, serum creatinine, blood urea nitrogen, cystatin C and BNP decreased, left ventricular ejection fraction increased, There was statistical significance (P <0.05). Conclusion CRRT plays an important role in the treatment of refractory cardiorenal syndrome, which can improve heart and kidney function and improve the quality of life.