The flux-weighted average cross sections of natCd(γ,xn)115g,m,111m,109,107,105,104Cd and natCd(γ,x)113g,112,111g,110mAg reactions were measured at the bremsstrahlung end-point energies of 50 and 60 MeV.The activa-tion and off-line γ-ray spectrometric technique was carried out using the 100 MeV electron linear accelerator at the Pohang Accelerator Laboratory,Korea.The natCd(γ,xn) reaction cross sections as a function of photon energy were theoretically calculated using the TALYS-1.95 and the EMPIRE-3.2 Malta codes.Then,the flux-weighted average cross sections were obtained from the theoretical values of mono-energetic photons.These values were compared with the flux-weighted values from the present study and were found to be in general agreement.The measured ex-perimental reaction cross-sections and integral yields were described for cadmium and silver isotopes in the natCd(γ,xn)115g,m,111m,109,107,105,104Cd and natCd(γ,x)113g,112,111g,110mAg reactions.The isomeric yield ratio (IR) of 115g,mCd in the natCd(γ,xn) reaction was determined for the two bremsstrahlung end-point energies.The measured isomeric yield ra-tios of 115g,mCd in the natCd(γ,xn) reaction were also compared with the theoretical values of the nuclear model codes and previously published literature data of the 116Cd(γ,n) and 116Cd(n,2n) reactions.It was found that the IR value increases with increasing projectile energy,which demonstrates the characteristic of excitation energy.However,the higher IR value of 115g,mCd in the 116Cd(n,2n) reaction compared to that in the 116Cd(γ,n) reaction indicates the role of compound nuclear spin alongside excitation energy.