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本文报道了异稻瘟净农药的毒性,大鼠经口LD_(50)雌性为524.8mg/kg,雄性为692mg/kg;雌性大鼠经皮LD_(50)为2625mg/kg;小鼠经口染毒的蓄积系数>5。Ames试验TA_(100)和TA_(98)菌株及小鼠骨髓多染红细胞微核试验均为阴性。车间空气中异稻瘟净的最高浓度为0.94mg/m~3,95%农度0.186mg/m~3,在这样的环境下生产对工人健康未发现不良作用。建议车间空气中最高容诈浓度为1.0mg/m~3(皮)。
In this paper, the toxicity of nematamycin alone was reported. The LD50 of female rats was 524.8 mg / kg and the male was 692 mg / kg. The LD50 of female rats was 2625 mg / kg. Exposure to the accumulation coefficient> 5. Ames test TA_ (100) and TA_ (98) strains and mouse bone marrow erythrocytes micronucleus test were negative. The highest concentration of different rice blast in the air of the workshop was 0.94mg / m ~ 3,95% of farmland 0.186mg / m ~ 3. No adverse effects on the workers’ health were found in this kind of environment. It is recommended that the maximum level of cheat concentration in the workshop air is 1.0mg / m ~ 3 (skin).