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牙周病是一种病因复杂的微生物感染性疾病,并且与多种疾病密切相关。抗菌药物是牙周病治疗的重要手段之一,牙周局部抗菌缓控释制剂具有许多优越性,其应用也取得了较好的临床效果,显示出良好的应用前景。该文就抗菌药物在牙周病治疗中的地位,牙周局部抗菌缓控释制剂的优点、释药原理和类型、现有制剂和应用效果、面临的问题和展望等作一综述。
Periodontal disease is a complex infectious microbial disease, and is closely related to a variety of diseases. Antibacterials is one of the important means of periodontal therapy. Periodontal topical antibacterial sustained-release preparation has many advantages and its application has also achieved good clinical results, showing good application prospects. This article reviews the status of antimicrobial agents in the treatment of periodontal disease, the advantages of local periodontal antimicrobial sustained-release preparations, the principles and types of drug release, the effectiveness of existing agents and their application, the problems they face and their prospects.