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目的探讨评估心血管疾病风险及预后的新方法。方法从国外文献中发现一种新的无创测量心血管危险因素的手段——踝肱指数(ABI)正在受到关注,参照其方法原理进行临床研究。结果研究人群ABI值明显低于健康人群(P<0.01);研究人群ABI<9男女之间无差异,而ABI平均值男性明显低于女性,两者之间有明显差异(P<0.05)。Logistic回归分析研究人群ABI减低的危险因素,男性为年龄、糖尿病、高血压、吸烟;女性为年龄、糖尿病、吸烟。结论本研究条件要求简单,重复性好,临床患者多见,无需动物实验,属无创性检查,患者易接受,适用于基层医院预和大规模筛查,对预测心血管病具临床意义。
Objective To explore a new method to assess the risk and prognosis of cardiovascular diseases. Methods A new noninvasive means of measuring cardiovascular risk factors - ankle brachial index (ABI) is finding its attention in foreign literature and its clinical research is guided by its methodology. Results The ABI of the study population was significantly lower than that of the healthy population (P <0.01). There was no difference between the study population and the ABI <9, but the average ABI was significantly lower than that of the female. There was a significant difference between the two (P <0.05). Logistic regression analysis of the risk factors for ABI reduction in the population, men were age, diabetes, hypertension, smoking; women were age, diabetes, smoking. Conclusions The study conditions are simple, good repeatability, clinical patients are more common, without animal experiments, is a noninvasive examination, the patient is easy to accept, suitable for large-scale screening of grass-roots level hospitals for the clinical prediction of cardiovascular disease.