目的考察噢类化合物结构与抗癌活性间的关系。方法设计了一种合成噢的简便方法并合成了 4个噢类化合物 ,对产物进行了海虾幼虫致死性生物测定。结果发现 6 羟基噢有很强的抗癌活性。结论其活性与环上羟基数目有关。 Objective To investigate the relationship between the structure of aurones and anticancer activity. Methods A simple method for the synthesis of aurones was designed and four aurones were synthesized. The products were subjected to the lethal bioassay of shrimp larvae. The results showed that 6 hydroxy arsenic has a strong anti-cancer activity. Conclusions The activity is related to the number of hydroxyl groups on the ring.