脂代谢紊乱是儿童肾脏疾病进程中常见的并发症,不仅会增加成人期心血管疾病的危险性,而且还可加重原有肾脏损害,尤其是顽固性高脂血症,可能对肾病预后产生决定性的影响。为增加对肾病进程中脂代谢紊乱的认识,文章综述了其发生机制、临床特点、对“病肾”的影响以及治疗措施。 Lipid metabolism disorder is a common complication of childhood kidney disease process, not only increases the risk of cardiovascular disease in adults, but also aggravates the original renal damage, especially refractory hyperlipidemia, may have a decisive prognosis for nephropathy Impact. In order to increase the understanding of the disorder of lipid metabolism in the process of nephropathy, the article reviewed the mechanism of its occurrence, clinical features, the impact on the “kidney disease” and treatment measures.