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目的观察氟哌噻吨美利曲辛(deanxit)联合萨氏扩张术治疗食管吻合口良性狭窄的临床效果。方法食管-贲门癌术后吻合口良性狭窄患者46例,随机均分为两组:B组仅给予萨氏扩张器扩张;A组在扩张治疗的基础上加用氟哌噻吨美利曲辛口服,每天早、中各1片,至首次扩张术后3个月。随访3个月,比较两组的临床疗效。结果 A组患者吻合口狭窄扩张术的有效率高于B组(95.65%vs.73.91%)(P<0.01),扩张次数减少,术后胸骨后疼痛发生率降低(P<0.05)。结论氟哌噻吨美利曲辛能通过缓解患者的焦虑、抑郁状态,有效改善食管吻合口良性狭窄扩张术的治疗效果。
Objective To observe the clinical efficacy of dextran combined with saxophone in the treatment of benign esophageal stricture. Methods Forty-six patients with anastomotic benign esophageal and cardiac resections were randomly divided into two groups: Group B received only Sardis’ dilator expansion; Group A was treated with dropenthixol and melitracen Services, morning and evening, each one, to the first expansion after 3 months. Follow-up 3 months, compared the clinical efficacy of the two groups. Results The effective rate of anastomotic stenosis in group A was higher than that in group B (95.65% vs.73.91%) (P <0.01). The number of dilatation decreased and the incidence of post-sternal pain decreased (P <0.05). Conclusion flupentixol and melitracen can effectively relieve the treatment of benign esophageal stricture by relieving anxiety and depression of patients.