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目的分析妊娠期高血压孕妇的血脂水平变化和特点。方法 80例妊娠期高血压孕妇作为研究组,健康孕妇80例作为对照组。抽取孕妇静脉血采用酶法测定血脂水平,并在组间平行比较。结果与对照组比较,妊娠期高血压、轻度子痫前期、重度子痫前期患者的总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白B(Apo B)水平明显增高(P<0.05);妊娠期高血压、轻度子痫前期、重度子痫前期患者的载脂蛋白A1(Apo A1)水平分别为(1.61±0.22)、(1.64±0.27)、(1.64±0.32)g/L,均低于对照组的(1.88±0.35)g/L,差异有统计学意义(P<0.05)。结论和健康孕妇相比,妊娠期高血压孕妇的血脂水平发生明显变化,应加强血脂监测,以利于开展干预和防治工作。
Objective To analyze the changes and characteristics of blood lipid levels in pregnant women with hypertensive disorders. Methods Eighty pregnant women with gestational hypertension were selected as study group and 80 healthy pregnant women as control group. Extract pregnant women venous blood enzymatic determination of lipid levels, and parallel comparison between groups. Results Compared with the control group, the levels of TC, TG, LDL-C, apolipoprotein (P <0.05). The levels of Apo A1 in gestational hypertension, mild preeclampsia and severe preeclampsia were (1.61 ± 0.22), (1.64 ± 0.27) and (1.64 ± 0.32) g / L, respectively, which were significantly lower than those in the control group (1.88 ± 0.35) g / L (P <0.05). Conclusion Compared with healthy pregnant women, blood lipid levels of pregnant women with gestational hypertension have changed significantly, and blood lipid monitoring should be strengthened to facilitate intervention and prevention.