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目的探讨米索前列醇联合缩宫素在剖宫产术后出血中的应用效果。方法以2009年11月～2010年4月于我院的剖宫产孕妇124例为研究对象,遵照知情同意原则随机分为两组,对照组60例单纯应用缩宫素预防产后出血,观察组64例采用米索前列醇联合缩宫素预防产后出血。观察两组产后2h、24h内出血量以及不良反应发生情况。结果观察组产后2h、24h内出血量均明显少于对照组,组间差异有统计学意义(P<0.05);两组均无明显不良反应发生。结论米索前列醇联合缩宫素在剖宫产术后出血中的应用效果满意,且无明显不良反应发生,值得临床关注。
Objective To investigate the effect of misoprostol combined with oxytocin on hemorrhage after cesarean section. Methods A total of 124 pregnant women undergoing cesarean section in our hospital from November 2009 to April 2010 were selected and randomly divided into two groups according to the principle of informed consent. 60 cases of control group were treated with oxytocin alone to prevent postpartum hemorrhage. The observation group 64 cases of misoprostol combined with oxytocin to prevent postpartum hemorrhage. Two groups of postpartum 2h, 24h bleeding and adverse reactions were observed. Results The amount of hemorrhage in observation group was significantly less than that in control group within 2 h and 24 h postpartum. The difference between the two groups was statistically significant (P <0.05). No adverse reactions occurred in both groups. Conclusion Misoprostol combined with oxytocin in cesarean section postoperative bleeding in the application of satisfactory results, and no significant adverse reactions, it deserves clinical attention.