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目的探讨甲基强的松龙治疗儿童肾病综合征伴急性肾功能衰竭的疗效。方法 100例肾病综合征伴急性肾功能衰竭患儿随机分为观察组(50例)与对照组(50例),对照组患儿给予强的松口服,观察组患儿给予甲基强的松龙冲击疗法,对比分析两组患儿的疗效。结果 1观察组患儿激素敏感的比例显著高于对照组患儿,差异有统计学意义(P<0.05);2观察组患儿复发率显著低于对照组,差异有统计学意义(P<0.05)。结论甲基强的松龙治疗儿童肾病综合征伴急性肾功能衰竭的疗效确切,复发率低,值得临床推广应用。
Objective To investigate the efficacy of methylprednisolone in the treatment of children with nephrotic syndrome and acute renal failure. Methods 100 cases of children with nephrotic syndrome and acute renal failure were randomly divided into observation group (50 cases) and control group (50 cases), the control group was given prednisone orally, the observation group was given methylprednisone Long impact therapy, comparative analysis of the efficacy of two groups of children. Results 1 The proportion of hormone-sensitive children in the observation group was significantly higher than that of the control group (P <0.05). The relapse rate of the observation group was significantly lower than that of the control group (P < 0.05). Conclusion Methylprednisolone treatment of children with nephrotic syndrome and acute renal failure has definite curative effect and low recurrence rate, which is worthy of clinical application.