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目的探讨心肌梗死患者血脂、血尿酸、纤维蛋白原和血小板参数变化情况及其意义,为临床提供依据。方法 228例心肌梗死患者为MI组;选择同期在某院门诊体检、排除肝、肾、心、脑等器质性疾病的患者228例组成对照组,比较两组的血脂、血尿酸、纤维蛋白原和血小板参数指标。结果 MI组患者的TCH、TG、LDL-C、APOB、UA、Lp、Fib、MPV和PDW较正常组升高,差异有统计学意义(P﹤0.05)。MI组HDL-C、APOA1和PCT较正常组降低,差异有统计学意义(P﹤0.05)。结论血脂、血尿酸、纤维蛋白原级血小板参数能够增加MI的发生率,因此针对这些因素进行干预,可以有效预防和对症治疗MI,提高患者的生存质量和治愈率,值得临床借鉴。
Objective To investigate the changes of serum lipids, serum uric acid, fibrinogen, platelet parameters and their significance in patients with myocardial infarction and provide evidence for their clinical application. Methods One hundred and eighty-eight patients with myocardial infarction were treated with MI. Two hundred and eighty-eight patients with organic disease such as liver, kidney, heart, brain and so on who were diagnosed in a hospital during the same period were selected as the control group. Blood lipids, serum uric acid, fibrin Original and platelet parameters. Results The levels of TCH, TG, LDL-C, APOB, UA, Lp, Fib, MPV and PDW in MI group were significantly higher than those in normal group (P <0.05). HDL-C, APOA1 and PCT in MI group were lower than those in normal group, with statistical significance (P <0.05). Conclusion Serum lipids, serum uric acid and fibrinogen platelet parameters can increase the incidence of MI. Therefore, intervention of these factors can effectively prevent and treat symptomatic MI and improve the quality of life and cure rate of patients, which is worthy of clinical reference.