骨巨细胞瘤是一种具有局部侵袭性、恶性潜能的病变;可能来源于未分化间充质细胞;按照间质细胞和多核巨细胞的异型程度分为三级;采用外科手术治疗是首选。发生于上颌骨者较罕见,一般选择肿瘤外扩大切除上颌骨,(同期行骨移植或二期赝复体修复)。 Giant cell tumor of the bone is a locally aggressive and malignant lesion; it may originate from undifferentiated mesenchymal cells; it is classified into three stages according to the abnormality of stromal cells and multinucleated giant cells; surgical treatment is the first choice. Occurred in the upper jaw are rare, the general choice of expansion of the tumor outside the maxillary resection (simultaneous bone graft or second prosthesis repair).