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目的探讨糖尿病周围神经病变相关危险因素分析及临床治疗效果评价。方法选取我院收治的195例糖尿病患者为研究对象，分为DPN组88例和非DPN组107例，比较分析两组患者相关危险因素，并采用血塞通联合α-硫辛酸对DPN患者进行治疗，观察治疗疗效。结果 DNP组病程、HbAlc、FPG、尿A/C、2hPG均明显高于非DNP组；DPN患者总疗效88.64%，神经传导速度明显高于治疗前。结论糖尿病周围神经病变与病程、HbAlc、FPG、尿A/C、2hPG相关；血塞通联合α-硫辛酸能有助于改善神经传导速度，提高治疗效果。“,”Objective To evaluate the analysis on the related risk factors for diabetic peripheral neuropathy and clinical therapeutic ef ect. Methods We selected 195 cases of diabetic patients in our hospital as the research object, is divided into 88 cases in DPN group and non DPN group 107 cases, comparative analysis of related risk factors of two groups of patients, and the use of the DPN patients were treated with Xuesaitong with lipoic acid, observation of curative ef ect of treating. Results In group DNP, HbAlc, FPG course, urinary A/C, 2hPG were significantly higher than that in non DNP group; 88.64% of the total curative ef ect of DPN patients, nerve conduction velocity was significantly higher than that before treatment. Conclusion Diabetic peripheral neuropathy and course of disease, HbAlc, FPG, urine A/C, 2hPG related;Xuesaitong with lipoic acid can help to improve the nerve conduction velocity, improve the treatment ef ect.