研究肠易激综合征 (IBS)患者直肠肛管压力的变化。应用美国Sandhill公司提供的BIOLAB消化道压力检测仪及固态压力传感器导管 ,对 43例明确诊断为IBS患者及 2 0名正常人进行直肠肛管压力检测 ,观察各参数的改变。结果IBS患者腹泻组的FSV、DSV、DUSV、MTV均较正常对照组低 ,其中DSV、DUSV和MTV与对照组比较有显著性差异 (P <0 0 1) ,便秘组的FSV、DSV、DUSV及MTV均较对照组高 ,其中FSV、DSV和DUSV和对照组比较有显著性差异 (P <0 0 1) ;IBS患者腹泻组的RRP、ARP及MSQP较对照组高 ,ARPD较对照组低 ;便秘组的RRP、ARP及ARPD均较对照组高 ,MSQP较对照组低 ;ISB患者腹泻组、便秘组的ARIR量均高于对照组且有显著性差异 (P <0 0 1) ;IBS患者腹泻组的顺应性降低而便秘组的顺应性增高 (P <0 0 1)。提示IBS患者的排便功能有不同程度的异常 To study the changes of rectal anal canal pressure in patients with irritable bowel syndrome (IBS). 43 cases of IBS patients and 20 normal controls were examined with the BIOLAB Gastrointestinal Pressure Monitor and Solid State Pressure Sensor catheter provided by Sandhill Company in the United States. The anorectal pressure was measured and the changes of parameters were observed. Results The FSV, DSV, DUSV and MTV of diarrhea patients in IBS group were lower than those in normal control group. DSV, DUSV and MTV were significantly different from those in control group (P <0.01) And MTV were higher than those in the control group, of which the FSV, DSV and DUSV were significantly different from the control group (P <0.01); the RRP, ARP and MSQP in the diarrhea group were higher than those in the control group ; The RRP, ARP and ARPD in constipation group were higher than those in control group and MSQP was lower than that in control group. ARIR in diarrhea group and constipation group were significantly higher than those in control group (P <0.01); IBS Patients with diarrhea compliance decreased constipation group compliance (P <0.01). Tip IBS patients have varying degrees of defecation dysfunction