美国ＦＤＡ批准了ＳａｌｉｘＰｈａｒｍａｃｅｕｔｉｃａｌｓ公司的巴柳氮二钠 (ｂａｌｓａｌａｚｉｄｅｄｉ Ｎａ ,Ｃｏｌａｚａｌ) ,用于治疗轻到中度活动期溃疡性结肠炎 ,这是一种慢性和致衰弱性胃肠道炎性疾病。巴柳氮二钠是一种 5 ＡＳＡ的无磺胺前药 ,是近 10年来ＦＤＡ The U.S. FDA approved Salix Pharmaceuticals’ balsalazidedi Na (Colazal) for the treatment of mild to moderate active ulcerative colitis, a chronic and debilitating gastrointestinal inflammatory disease. Balsalazide disodium is a 5 ASA sulfasalazine-free prodrug that has been used by FDA for nearly 10 years