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近年来对癌症患者进行的化疗变化迅速。新药不断涌现,被确认的药物正在更频繁地被采用,或联合应用,用较高的剂量,并通过新的给药途径。结果是患者的存活率增加,同时药物引起的毒性作用也逐渐增多。眼部副作用并不少见,可以极大地影响生活质量。各科医生越来越多地遇到癌症化疗病人需要处理。认识抗癌药物对眼部的毒性作用,才能恰当地进行处理。本文综述了抗癌药物对眼部的毒性作用、特别是其临床过程、发病机理,以及预防和治疗。
Chemotherapy has rapidly changed in cancer patients in recent years. New drugs are constantly emerging, and confirmed drugs are being used more frequently, either in combination, at higher doses, and by new routes of administration. The result is an increase in patient survival and a concurrent increase in the toxic effects of the drug. Eye side effects are not uncommon, can greatly affect the quality of life. Doctors increasingly encounter cancer chemotherapy patients need to deal with. Awareness of anti-cancer drugs on the role of the eye can be properly handled. This article reviews the toxic effects of anticancer drugs on the eye, especially its clinical course, pathogenesis, and prophylaxis and treatment.