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作者研究了肝癌患者肿瘤浸润淋巴细胞（ＴＩＬ）的体外分离、扩增培养和临床治疗，其目的是寻求癌症术后综合治疗更为有效的方法。结果表明，１２例用于ＴＩＬ培养的肿瘤组织重量平均４．８ｇ，细胞数５．８×１０￣７，培养时间３１．８天，最大扩增倍数１０００倍。ＬＡＫ上清液能显著促进ＴＩＬ的扩增培养。本组对１０例患者进行了ＴＩＬ的临床治疗，采用了经肝动脉的输注途径，回输细胞量为４×１０￣８～１．１×１０￣（１０）肝癌ＴＩＬ还显示对靶细胞有明显杀伤活性。
The authors studied the in vitro isolation, expansion, and clinical treatment of tumor-infiltrating lymphocytes (TIL) in patients with hepatocellular carcinoma. The purpose was to seek a more effective method for postoperative comprehensive treatment of cancer. The results showed that the weight of the 12 tumor tissues used for TIL culture was 4.8 g on average, the number of cells was 5.8×10 ̄7, the culture time was 31.8 days, and the maximum amplification was 1000 times. The LAK supernatant significantly promoted TIL expansion culture. In this group, 10 patients underwent clinical treatment of TIL using the transfusion pathway through the hepatic artery. The amount of reinfused cells was 4×10 ̄ 8 to 1.1×10 ̄ (10). Liver TIL also showed target cell Has significant killing activity.