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对脊髓灰质炎(简称脊灰)三价疫苗(TOPV)在冷链运转过程逐级进行效价监测,及时发现和改进冷链运转中存在的问题,对提高TOPV免疫成功率具有重要意义。为此,我们于1989～1992年每年7月份冷链运转时,按地→县→乡→村接种点逐级采集同一批号样品各10粒,放入冷藏包内,及时送省防疫站,按卫生部《计划免疫技术管理规程》规定的方法,进行效价测定,以效价≥5,63LogTCID_(50)/人份为合格。在4年中共抽查7个批号71份样品,合格65份,合格率为91.55％,其中1989年合格率较低,为
Monitoring the potency of poliovirus (poliovirus) trivalent vaccine (TOPV) step by step in the process of cold chain operation and discovering and improving the problems in the cold chain operation in a timely manner is of great significance to improve the success rate of TOPV immunization. To this end, we in 1989 ~ 1992 each year in July when the cold-chain operation, according to ground → County → Township vaccination point by level to collect the same batch of 10 samples, placed in a cold pack, timely delivery to the provincial epidemic prevention station, press Ministry of Health, “Immunization Technology Management Regulations” provisions of the method, the determination of potency to potency ≥ 5,63 LogTCID_ (50) / person as qualified. In 4 years, a total of 71 batches of 71 batches of samples were selected, of which 65 were qualified, with a pass rate of 91.55%, of which, the passing rate in 1989 was low, which was