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在1岁以内的婴儿中,对禽蛋的过敏反应是最常见的IgE介导的食物超敏反应。流行性腮腺炎-麻疹-风疹(MMR)疫苗中的流行性腮腺炎和麻疹病毒是在禽胚中减毒的,该疫苗含有微量禽蛋产物。美国儿科学会推荐对三种疫苗进行皮试以确定对禽蛋过敏儿童免疫接种MMR疫苗的安全性。本文旨在评价1∶100MMR疫苗皮试阴性对预测此类儿童接种疫苗安全性的可靠性。作者选择了17名可能有禽蛋过敏史并需作常规MMR免疫接种的15~36月龄幼儿。有皮肤划痕现象、新霉素过敏史或明显心脏病的儿童均不予评价。对禽蛋过敏表现为摄入禽蛋后2小时内发生荨麻疹、恶心、
Among babies under one year of age, allergic reactions to eggs are the most common IgE-mediated food hypersensitivity reactions. Mumps and measles viruses in mumps-measles-rubella (MMR) vaccines are attenuated in the poultry embryo, which contain traces of egg products. The American Academy of Pediatrics recommends skin tests of three vaccines to determine the safety of immunized MMR vaccines against egg-allergic children. This article aims to evaluate the reliability of a 1: 100 MMR vaccine skin test negative for predicting the safety of this type of child vaccination. The authors selected 15 children aged 15-36 months who had a history of egg allergy and would need to undergo regular MMR immunization. Children with skin scratches, a history of neomycin allergy or overt heart disease were not evaluated. Hypersensitivity to eggs is manifested within 2 hours after ingestion of eggs, urticaria, nausea,