本文探讨了硫酸链霉素注射液(500,000 u/2 ml)在不同温度下两种处方降解的变色规律。由实验数据归纳出,注射液的变色规律可表示为回归方程:(A-A_0)=a+bt~(1,5)注射液的变色速率方程为:dA/dt=k(A-A_0-a)~(1/3),注射液的变色不是一个简单级数的反应。用经典恒温法和初均速法进行了稳定性加速试验,结合Weibull分布拟合法计算了注射液的贮存期,均为20个月。 This article discusses the color change rule of streptomycin sulfate injection (500,000 u / 2 ml) at different temperatures. According to the experimental data, the law of discoloration of injection can be expressed as regression equation: The color change rate equation of (A-A_0) = a + bt ~ (1,5) injection is: dA / dt = a) ~ (1/3), the discoloration of the injection is not a simple series of reactions. The stability accelerated test was carried out by the classical thermostat method and the average initial velocity method, and the storage period of the injection solution was calculated by Weibull distribution fitting method, both of which were 20 months.