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目的总结采用氯米芬(CC)联合尿促性素(HMG)促排卵治疗女性不孕症79例的成功经验。方法回顾分析2005年6月～2008年5月采用CC+HMG促排卵治疗女性不孕症成功妊娠79例的不孕原因、治疗方法和妊娠结局。结果女性不孕症的原因以排卵障碍为主,共55例,占69.6%,其次为卵管因素15例,占19%。妊娠结局为:足月产56例,早产2例,流产13例,异位妊娠8例;分别占70.9%,2.5%,16.5%及10.1%。多胎妊娠4例,占5.1%。促排卵疗程与妊娠相关,1～3周期治疗成功者69例,占87.3%。结论处理女性不孕症重在查清楚不孕原因,针对原因进行治疗可收到良好的效果,促排卵治疗是不孕症的主要治疗方法,卵管因素促排卵使一侧输卵管通畅者增加妊娠机会。但需注意防止卵巢过度刺激综合症(OHSS)、流产、异位妊娠及多胎妊娠等并发症。
Objective To summarize the successful experience of treating female infertility with clomiphene citrate (CC) combined with urinary hoggin (HMG) ovulation induction. Methods Retrospective analysis of June 2005 ~ May 2008 CC + HMG ovulation treatment of female infertility success of 79 cases of infertility causes of infertility, treatment and pregnancy outcomes. Results The main reason of female infertility was ovulation disorder, with 55 cases (69.6%) followed by 15 cases of oviduct (19%). Pregnancy outcomes were: full-term birth in 56 cases, premature birth in 2 cases, abortion in 13 cases and ectopic pregnancy in 8 cases, accounting for 70.9%, 2.5%, 16.5% and 10.1% respectively. 4 cases of multiple pregnancy, accounting for 5.1%. Ovulation course of pregnancy and pregnancy-related, 1 to 3 cycles 69 cases of successful treatment, accounting for 87.3%. Conclusion Treatment of female infertility focus on identifying the causes of infertility, for treatment of causes can receive good results, ovulation induction treatment is the main treatment of infertility, ovulation factors to promote ovulation side of the tubal patency to increase pregnancy opportunity. However, care should be taken to prevent complications such as ovarian hyperstimulation syndrome (OHSS), miscarriage, ectopic pregnancy and multiple pregnancy.