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经调查并分析美国达拉斯道医院51例药源性发烧患者和英国文献报道的93例同样的病例后发现:停药是控制药源性发烧的唯一有效途径。药源性发烧通常是某种药物副作用唯一或最突出的表现,一般情况下并不伴随其它严重的全身性毒性反应。由于药源性发烧的出现,达拉斯道医院的51名病人接受住院治疗的时间平均延长8.7d。高烧常常伴随着寒颤,因此难于将药源性发烧同细菌性感染及其病因相区别。分析患者的临床治疗情况发现,绝大多数药源性发烧起因于抗菌药物,发现使用抗癌药物也能导致高烧。在已经调查和分析的病例中,发现引起发烧的药物是: 心血管系统药物:α-甲基多巴、奎尼丁、普
After investigating and analyzing 51 cases of drug-induced fever in Dallas Road Hospital of the United States and 93 cases reported in the British literature, it was found that withdrawal was the only effective way to control drug-induced fever. Drug-induced fever is usually the only or most prominent manifestation of the side effects of a drug and is not associated with other serious systemic toxicities under normal circumstances. Due to drug-induced fever, 51 patients at Dallas Road Hospital were hospitalized for an average of 8.7 days. High fever often accompanied by chills, it is difficult to drug-induced fever and bacterial infections and their causes are different. Analysis of the clinical treatment of patients found that the vast majority of drug-induced fever caused by antibiotics, found that the use of anti-cancer drugs can also lead to high fever. Among the cases that have been investigated and analyzed, the drugs that cause fever are found to be: cardiovascular system drugs: alpha-methyldopa, quinidine,