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目的分析邢台市2009-2011年疑似预防接种异常反应(AEFI)的发生特征,评价AEFI监测系统运转情况、预防接种服务质量和疫苗的安全性。方法根据《疑似预防接种异常反应信息管理系统》报告数据。用描述性流行病学方法进行分析。结果 2009-2011年全市使用疫苗35种,32种疫苗报告了2064例AEFI,其中一般反应占92.30%,异常反应占7.17%,偶合症占0.10%,心因性反应占0.44%。无细胞百白破疫苗AEFI发生数最多,占总例数的31.77%,AEFI的发生以0岁组最多,占62.87%,以发热、局部红肿、硬结为主要临床表现。结论掌握AEFI的发生特征,加强宣传教育,加强预防接种门诊规范化建设,提高接种对象或监护人对AEFI的正确认识,可减少AEFI对免疫规划工作带来的负面影响。
Objective To analyze the incidence of suspected AEFI in Xingtai City from 2009 to 2011, assess the operation of AEFI monitoring system, and to prevent the quality of vaccination services and the safety of vaccines. Methods According to “suspected vaccination abnormal response information management system” report data. Descriptive epidemiological analysis. Results 35 vaccines were used in the city from 2009 to 2011, and 2064 AEFIs were reported from 32 vaccines, of which 92.30% were general reactions, 7.17% were abnormal reactions, 0.10% were coupled diseases and 0.44% were cardiological reactions. The number of AEFI cell-free vaccine was the highest, accounting for 31.77% of the total cases. The incidence of AEFI was highest in 0-year-old group, accounting for 62.87%. The main clinical manifestations were fever, local swelling and induration. Conclusions Grasp the characteristics of AEFI, strengthen publicity and education, strengthen the standardized construction of vaccination clinics and improve the correct understanding of AEFI for vaccinated subjects or guardians, which can reduce the negative impact of AEFI on immunization planning work.