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根据国家科委重症肝炎攻关组的计划,我校病毒性肝炎研究所对25例经肝穿活检证实诊断的亚急性重症肝炎,采用免疫调节,纠正调理素功能缺陷、改善微循环、纠正氨基酸代谢紊乱等治疗措施,结果存活12例,病死率已降至52%,与国内外比较,是先进的。 他们特别对纠正重症肝炎非特异性免疫功能进行了研究,建立应用体外法测定胸腺肽的合适剂量,发现治疗后抑制性细胞功能恢复正常者,预后较好。采用反复输入新鲜血浆,纠正调理素功能缺陷,可以减少继发感染,降低病死率,而陈旧血浆无效。他们还采用体内外监测方法,合理调整血浆用量。并对胰高血糖素
According to the plan of the State Science and Technology Commission for Severe Hepatitis, 25 cases of subacute severe hepatitis diagnosed by liver biopsy are treated with our Institute of Viral Hepatitis. Immunomodulation is used to correct defects in opsonin, improve microcirculation and correct amino acid metabolism Disorder and other treatment measures, the results of survival in 12 cases, the mortality rate has dropped to 52%, compared with at home and abroad, is advanced. In particular, they studied the correction of non-specific immune function in severe hepatitis and established a suitable dose for the determination of thymosin by an in vitro method. The patients were found to have normal inhibitory function after treatment, and the prognosis was good. The use of repeated input of fresh plasma to correct the deficiencies of opsonin, can reduce secondary infection, reduce mortality, while the old plasma is invalid. They also use in vitro and in vivo monitoring methods to rationally adjust plasma levels. And glucagon