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目的了解清新县中小学生乙型肝炎病毒感染状况,为制定有效的防控措施提供科学依据。方法采取整群抽样的方法,对辖区内中小学校部分在校学生采集全血分离血清,用酶联免疫吸附试验(ELISA)检测血清中乙型肝炎表面抗原(HBsAg)、表面抗体(抗-HBs)。结果共采集学生血56 583份,HBsAg阳性率为4.04%,抗-HBs阳性率为30.04%;小学生HBsAg阳性率明显低于中学生;县城不同性别中小学生HBsAg阳性率、抗-HBs阳性率差异无统计学意义;不同片区的学生HBsAg阳性率差异有统计学意义。结论今后应加大乙型肝炎防治知识的宣传力度,加强在校中小学生乙型肝炎疫苗接种工作,提高其免疫水平。
Objective To understand the status of hepatitis B virus infection among primary and secondary school students in Qingxin County and provide a scientific basis for effective prevention and control measures. Methods The method of cluster sampling was used to collect serum from whole blood in some primary and secondary school students in the area. Serum levels of HBsAg and anti-HBs were detected by enzyme-linked immunosorbent assay (ELISA) ). Results A total of 56 583 students were enrolled in this study. The positive rate of HBsAg was 4.04% and the positive rate of anti-HBs was 30.04%. The positive rate of HBsAg in primary school students was significantly lower than that of secondary school students. There was no difference in HBsAg positive rate and anti-HBs positive rate among primary and secondary school students Statistical significance; HBsAg positive rate in different areas of the students was statistically significant difference. Conclusion In the future, we should step up publicity on knowledge of prevention and treatment of hepatitis B, strengthen hepatitis B vaccination among primary and secondary school students, and raise their immunization level.