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目的:了解梧州市食品及公共场所从业人员乙肝病毒感染状况,为卫生监督及乙肝防控提供依据。方法:取受检者静脉血,酶联免疫吸附试验(ELISA)测乙肝表面抗原(HBsAg)、e抗原(HBeAg),改良赖氏法测血清丙氨酸氨基转移酶(ALT)。结果:2005~2008年度参加体检的食品、公共场所从业及其岗前体检人员共71512人,HBsAg、HBeAg总阳性率分别为6.31%、1.55%,HBeAg占HBsAg阳性总比率为24.64%;3种检出率均呈逐年下降趋势且有统计学意义。年龄间检出率呈低年龄组向高年龄组逐一降低趋势,性别检出率男高于女,且年龄组间、性别间差异均有统计学意义。ALT总异常率0.28%;异常率年间波动在0.23%~0.37%之间,无统计学差异意义;而性别间,不同感染模式、无感染者之间,差异均具统计学意义。结论:乙肝病毒感染,尤其HBeAg阳性,对健康及作为传染源有很大的危险性,应予高度关注与重视。
Objective: To understand the status of hepatitis B virus infection among employees in food and public places in Wuzhou and to provide basis for health supervision and prevention and control of hepatitis B. Methods: Venous blood was taken from the subjects and HBsAg, e antigen (HBeAg) were measured by enzyme - linked immunosorbent assay (ELISA), and serum alanine aminotransferase (ALT) was measured by modified Raji method. Results: The total positive rate of HBsAg and HBeAg in the food, public places and pre-service medical staff from 2005 to 2008 were 6.31% and 1.55%, respectively, and the total HBsAg positive rate was 24.64%. Three The detection rate showed a declining trend year by year and was statistically significant. The detection rate was lower in the younger age group than in the older age group, and the male gender was higher than the female gender in the age group. There were significant differences between the age groups and between the sexes. The total abnormal rate of ALT was 0.28%. The abnormal rate fluctuated between 0.23% ~ 0.37% in the year, which had no significant difference. However, there was no significant difference between sexes, different modes of infection and no infection. Conclusion: Hepatitis B virus infection, especially HBeAg positive, is of great danger to health and infection source, and should be given high attention and attention.