手一口综合征是一种局限于手或指和同侧口周的单侧感觉障碍。该征最初被Sitting 归因于对侧顶叶的中央后回损害。此后,发现此种感觉障碍的特殊分布同丘脑,脑干损害有关。本文报道的三例手一口综合征,经高分辨的MRI 证实是由于对侧放射冠的小病灶所致。例1,男性56岁高血压患者,晨起发现左手麻木,麻木逐步发展到左侧口周.病后2天入院,血压176/86mmHg,智力、定向力正常,仅有的阳性 One-hand syndrome is a unilateral sensory disturbance that is confined to the hands or fingers and the ipsilateral periaqueductal circle. This sign was initially due to Sitting’s central posterior lesion affected by contralateral parietal lobe. Since then, the special distribution of such sensory disturbances has been found to be associated with damage to the thalamus and brainstem. The three cases of hand-mouth syndrome reported in this paper were confirmed by high-resolution MRI due to the small lesions of contralateral coronaries. Example 1, male 56-year-old hypertensive patients, the morning found the left hand numbness, numbness and gradually developed to the left side of the mouth .2 days after admission admitted to hospital, blood pressure 176 / 86mmHg, intelligence, orientation normal, only positive