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目的分析女性冠状动脉粥样硬化性心脏病 (CHD)患者危险因素与冠状动脉造影 (CAG)特点 ,提高对女性CHD的诊断率。方法对1 0 6例疑诊为CHD的女性患者行CAG后 ,分为CHD组和非CHD组 ,比较两组危险因素的数量、类型及其与冠状动脉病变程度的关系。结果女性CHD组发病年龄高 (P <0 .0 5) ,绝经者比例高 (90 .6 %与 80 .9%P <0 .0 1 ) ,合并高脂血症者CHD组显著高于非CHD组 (81 .3 %与40 .5%P <0 .0 0 5) ,合并两个及以上CHD危险因素者CHD显著增多 (67.2 %与 2 8.6% ,P <0 .0 5) ,而且 ,冠脉双支及三支病变者与单支者比较 ,合并两个及以上危险因素者为多 (69.8%与 61 .9% ,P <0 .0 5)。结论绝经和脂质异常是女性CHD的重要危险因素 ,而且 ,危险因素越多 ,CHD发病率越高 ,冠状动脉病变程度越重 ,说明CHD发病率及冠脉受累程度与危险因素多少正相关
Objective To analyze the risk factors and coronary angiography (CAG) in women with coronary atherosclerotic heart disease (CHD) and to improve the diagnostic rate of female CHD. Methods One hundred and six female patients with suspected CHD were divided into CHD group and non-CHD group. The number and types of risk factors and their relationship with coronary lesion degree were compared. Results The incidence of CHD group was higher (P <0.05), the proportion of menopause was higher (90.6% vs 80.9% P <0.01), and the CHD group with hyperlipidemia was significantly higher than that of non-CHD group CHD group (81.3% versus 40.5% P <0.05), CHD was significantly higher in those with two or more CHD risk factors (67.2% vs. 22.6%, P <0.05), and , Coronary artery disease, double coronary artery disease, and coronary artery disease were more common in two or more risk factors (69.8% vs 61.9%, P <0.05). Conclusions Menopause and dyslipidemia are important risk factors of CHD in women. Moreover, the more risk factors, the higher the incidence of CHD and the more severe coronary artery disease, indicating that the incidence of CHD and the degree of coronary artery involvement are positively correlated with risk factors