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目的:应用组织多普勒成像技术(tissue doppler imaging,TDI)测量三尖瓣环运动速度及时间间期指标评价AIDS患者右心功能,探讨组织多普勒评价AIDS患者右心功能的临床价值。方法:对72例AIDS患者行超声心动图检查,采集三尖瓣环瓣叶附着点处前、后、侧壁3个位点的TDI频谱,测量各位点的收缩期峰值速度(Vs)、舒张早期峰值速度(Ve)、舒张晚期峰值速度(Va),计算右心平均Vs、Ve、Va。同时测量三尖瓣环瓣叶附着点处侧壁位点时间间期指标(A线、B线),计算Tei指数。并与健康对照组进行对照分析。结果:病例组三尖瓣环各位点Vs、Ve、Va及Vs[(11.33±1.91)cm/s,(12.74±2.09)cm/s]、Ve[(11.69±2.41)cm/s,(15.17±3.05)cm/s]、Va[(10.61±2.45)cm/s,(12.71±3.18)cm/s]较对照组明显降低(P<0.05),右心Tei指数与对照组相比明显升高(0.41±0.11,0.30±0.16,P<0.05),差异具统计学意义。结论:AIDS患者可发生右心功能障碍。
OBJECTIVE: To evaluate the right heart function in AIDS patients by measuring the velocity and time interval of tricuspid annulus with tissue doppler imaging (TDI) and evaluate the clinical value of tissue Doppler in evaluating right heart function in AIDS patients. Methods: Seventy-two AIDS patients underwent echocardiography. The TDI spectra of three sites of the anterior, posterior and lateral walls of the tricuspid annulus were collected. The systolic peak velocity (Vs), diastolic Early peak velocity (Ve), late diastolic peak velocity (Va), right heart average Vs, Ve, Va. At the same time, the time interval index (A line and B line) of lateral wall site at tricuspid annulus attachment point was measured to calculate Tei index. And compared with healthy control group. Results: Vs, Ve, Va and Vs [(11.33 ± 1.91) cm / s, (12.74 ± 2.09) cm / s] and Ve [(11.69 ± 2.41) cm / (10.61 ± 2.45 cm / s, (12.71 ± 3.18) cm / s] was significantly lower than that of the control group (P <0.05), and the Tei index of the right heart was significantly higher than that of the control group High (0.41 ± 0.11,0.30 ± 0.16, P <0.05), the difference was statistically significant. Conclusion: Right heart dysfunction can occur in AIDS patients.