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目的观察新疆维吾尔族心血管病高危人群臂踝脉搏波速度(baPWV)与心血管病危险因素的相关性。方法连续收集148例维吾尔族心血管病高危患者,测量baPWV、身高、体重、腰围、血压、心率,采集病史并行血液生化检查。比较高baPWV组(≥1700cm/s)与低baPWV组(﹤1700cm/s)患者具有危险因素的个数和临床心脑血管事件发生情况的差异。结果与低baPWV组相比,高baPWV组心脑血管事件发生率较高(46.8%vs73.9%,P﹤0.01),心血管危险因素数目较多[(3.8±1.0)vs(4.7±1.1),P﹤0.001]。影响baPWV的因素主要为年龄(P﹤0.001)、收缩压(P﹤0.01)和脉压(P﹤0.05)。结论在维吾尔族心血管病高危人群中,baPWV较高的患者心脑血管事件发生率高,心血管危险因素多。年龄、收缩压和脉压是影响baPWV的独立危险因素。
Objective To investigate the relationship between brachial-ankle pulse wave velocity (baPWV) and cardiovascular risk factors in high-risk Uighur cardiovascular patients in Xinjiang Uygur Autonomous Region. Methods A total of 148 high-risk Uighur cardiovascular patients were collected. The baPWV, height, weight, waist circumference, blood pressure, heart rate and blood biochemistry were collected. The number of risk factors in patients with high baPWV (≥ 1700 cm / s) and low baPWV (<1700 cm / s) and the incidence of clinical cardiovascular and cerebrovascular events were compared. Results The incidence of cardiovascular events was higher in the high baPWV group than in the low baPWV group (46.8% vs 73.9%, P <0.01), and the number of cardiovascular risk factors was much higher (3.8 ± 1.0 vs 4.7 ± 1.1 ), P <0.001]. The main factors influencing baPWV were age (P <0.001), systolic pressure (P <0.01) and pulse pressure (P <0.05). Conclusions Among the Uighur high risk population of cardiovascular disease, patients with higher baPWV have a higher incidence of cardiovascular and cerebrovascular events and more cardiovascular risk factors. Age, systolic blood pressure, and pulse pressure were independent risk factors for baPWV.