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[目的]观察红花注射液联合激素和环磷酰胺治疗难治性肾病综合征的临床疗效观察。[方法]观察38例难治性肾病综合征患者用中药制剂红花注射液结合西药治疗前后肾功能、肝功、血脂、血常规、24h尿蛋白的对比。[结果]总有效率92.1%,缓解率73.68%(28例),部分缓解18.42%(7例),无效7.89%(3例)。[结论]红花注射液联合西药治疗难治性肾病综合征,减少激素的用量及副作用,增强疗效,缩短疗程,减少复发,防止反弹。
[Objective] To observe the clinical effects of safflower injection combined with hormone and cyclophosphamide in the treatment of refractory nephrotic syndrome. [Method] Observe the contrast of renal function, liver function, blood fat, blood routine and 24h urinary protein in 38 patients with refractory nephrotic syndrome before and after treatment with safflower injection combined with western medicine. [Results] The total effective rate was 92.1%, the remission rate was 73.68% (28 cases), the partial remission was 18.42% (7 cases), and the ineffective rate was 7.89% (3 cases). [Conclusion] The combination of safflower injection and western medicine in the treatment of refractory nephrotic syndrome can reduce the dosage and side effects of hormones, enhance the curative effect, shorten the course of treatment, reduce recurrence and prevent the rebound.