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尿中δ-氨基乙酰丙酸(简称ALA)测定对铅中毒诊断的价值,目前国内外看法不一。有人认为它远不如红细胞δ-氨基乙酰丙酸脱水酶(简称ALA-D)敏感;亦有人从尿ALA和血铅不相符合的角度,认为它不是一个良好的指标;但是,多数人都认为它和血铅、尿铅、尿粪卟啉以及空气中铅的浓度均有显著的相关,用于普查还是有一定价值,建议列为诊断依据之一。本文的目的,在于探讨尿ALA在铅中毒诊断中的价值,并和共他指标作一比较。
Urinary δ-aminolevulinic acid (ALA) determination of the value of lead poisoning diagnosis, at home and abroad have different views. Some people think it is far less sensitive than erythrocyte delta-aminolevulinic acid dehydratase (ALA-D); some people think it is not a good indicator from the point of view that urine ALA and blood lead do not match; however, most people think It is associated with blood lead, urinary lead, urinary coproporphyrin and air lead concentrations are significantly related to the census or have some value, it is recommended as one of the diagnostic basis. The purpose of this article is to investigate the value of urinary ALA in the diagnosis of lead poisoning and to compare it with that of other indicators.