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目的了解东营市对16～50岁人群进行免疫接种后的免疫效果,为制定乙型肝炎防治策略提供科学依据。方法从1 398名无免疫史的人群中随机抽取了409名乙肝表面抗原(HBsAg)、抗-HBs和乙肝核心抗体(抗-HBc)均为阴性人群,在完成3针免疫后进行抗-HBs阳性率分析。结果在完成三针次全程免疫后,阳性人数为374人,其中男性153人,阳性率为89.0%,平均抗体滴度276 mIU/ml;女性221人,阳性率93.3%,平均抗体滴度282.72 mIU/ml;总阳性率91.4%。结论广泛开展易感人群的免疫接种是控制乙肝发病的有效方法。
Objective To understand the immune effect of Dongying city after immunization for 16 ~ 50 years old population and provide a scientific basis for the development of hepatitis B prevention and control strategies. Methods A total of 409 hepatitis B surface antigen (HBsAg), anti-HBs, and hepatitis B core antibody (anti-HBc) were randomly selected from among 1 398 non-immunized individuals. All three were negative for anti-HBs Positive rate analysis. Results After the completion of three doses of subcutaneous whole immunization, the positive number of 374 people, of which 153 were male, the positive rate was 89.0%, the average antibody titer 276 mIU / ml; female 221, the positive rate of 93.3%, the average antibody titer of 282.72 mIU / ml; total positive rate of 91.4%. Conclusion Extensive immunization of susceptible populations is an effective way to control the incidence of hepatitis B.