一般应用测定体液内抗菌素的浓度的方法很多,但大多技术复杂,而且多应用血清。血清比之血浆及全血是人工改变过的生物学环境,而且所用血量也较多。作者采用全血并应用滤纸片法作实验。方法系自指尖将血滴於双层滤纸片上,经15—20分钟使均匀渗透并适当浓缩,然后 There are many ways to determine the concentration of antibiotics in body fluids. However, most of them are complicated in technology and use more serum. Serum than the plasma and whole blood is artificially changed biological environment, but also the use of more blood. The authors used whole blood and applied the filter paper method for experiments. Method is from the tip of the blood drops on the double filter paper, after 15-20 minutes so that uniform penetration and appropriate concentration, and then