Objective To investigate the association between APOB gene R532W polymorphism and the risk of coronary heart disease(CHD)in patients without lipid-lowering treatment and to analyze the interactions between the variation of R532W and different risk factors of CHD.Methods CHD and non-CHD were diagnosed according to coronary artery angiography(CAG)and/or coronary computed tomography angiogram(CTA)results,as well Objective To investigate the association between APOB gene R532W polymorphism and the risk of coronary heart disease (CHD) in patients without lipid-lowering treatment and to analyze the interactions between the variation of R532W and different risk factors of CHD. Methods CHD and non-CHD were diagnosed according to coronary artery angiography (CAG) and / or coronary computed tomography angiogram (CTA) results, as well