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对１０００例含消炎痛ＶＣｕ２００与１０００例对照组进行比较性研究。在２４个月末，每１００妇女净累积续用率分别为８３．２０与８３．３６，其中妊娠率分别为２．２０与１．４１（Ｐ＞０．０５）。脱落率在１２与１８个月时药环组较对照组高（Ｐ＜０．０５），２４个月时分别为８．８１／１００与６．６２／１００妇女，无显著性差别，但相对来讲药环组还是较对照组高。因症取出率对照组高于药环组（Ｐ＜０．０５）。主要原因是出血，具体表现在经量增多，经期延长与点滴出血。这三种现象两组之间Ｐ值均＜０．０１，药环与对照环避孕效果相似而药环基本解决了用ＩＵＤ的主要副反应出血问题。本文分析脱落率较高的可能原因，并对药环的装置进行了改进，用改进后的药环观察一年，脱落率有所下降。
Comparative study of 1000 cases of VCu200 containing indomethacin and 1000 cases of control group. At the end of 24 months, net cumulative renewal rates per 100 women were 83.20 and 83.36, respectively, with pregnancy rates of 2.20 and 1.41, respectively (P> 0.05). At 12 and 18 months, the rate of exfoliation was higher in the drug-eluting group than in the control group (P <0.05), with 8.81 / 100 and 6.62 / 100 women at 24 months, respectively, with no significant difference, but relative In terms of medicine ring group is still higher than the control group. The rate of removing the disease in the control group was higher than that in the drug group (P <0.05). The main reason is bleeding, the specific performance by the increase in volume, menstrual extension and drip bleeding. The P values of the three groups were all less than 0.01, similar to the contraceptive effect of the control and the control ring, while the drug ring basically solved the main side effects of bleeding with the IUD. This article analyzes the possible reasons for the high rate of shedding, and the improvement of the drug loop device, observed with a modified drug ring year, shedding rate decreased.