实验室内用杀虫剂对昆虫进行选择性试验成功地培养出抗性品系的例子有好几个,经遗传分析结果表明是多基因遗传所致,其中最著名的例子是黄猩猩果蝇(Drosophila melanogaster)对滴滴涕的抗性。与此相反,田间发现的抗性一般认为是由一个或只是极少几个基因引起的。这种简单的基因结构是与同样简单的抗性生物化学相一致的。这些抗性产生机制,一部分是活性部位变化,而大多数是解毒作用加强。 Selective testing of insects with insecticides in the laboratory There are several examples of successful resistant strains that have been shown to be polygenic due to genetic analysis. The best known example of this is Drosophila melanogaster) resistance to DDT. In contrast, the resistance found in the field is generally thought to be caused by one or just a few genes. This simple gene structure is consistent with equally simple resistance biochemistry. These resistance mechanisms, in part, are changes in the active site, most of which are detoxification enhancements.