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目的:对米非司酮与桂枝茯苓加减丸分别单独治疗及联合应用治疗子宫肌瘤的效果进行对比,观察疗效。方法:回顾总结66例子宫肌瘤患者诊治方案与疗效。22例口服米非司酮片;22例口服桂枝茯苓加减丸;22例同时服用两种药物,3组连续用药90d。检测子宫肌瘤体积以及血清卵泡刺激素、黄体生成素、雌激素及孕的浓度。结果:3组患者月经量、经期时间、痛经以及腰部酸胀等症状较治疗前明显改善,其中联合用药组月经量较其他两组减少更为明显。结论:米非司酮与桂枝茯苓加减丸联合用药治疗子宫肌瘤疗效优于单独用药,有临床推广价值。
OBJECTIVE: To compare the effects of mifepristone and Guizhi Fuling capsule on the treatment of uterine fibroids and the curative effect. Methods: The diagnosis and treatment of 66 cases of uterine fibroids were reviewed. 22 cases of oral mifepristone tablets; 22 cases of oral administration of Guizhi Fuling plus pills; 22 patients taking two drugs at the same time, three consecutive 90d. Detection of uterine fibroids volume and serum follicle stimulating hormone, luteinizing hormone, estrogen and pregnancy concentration. Results: The symptoms of menstruation, menstrual period, dysmenorrhea and soreness of waist in 3 groups were significantly improved than those before treatment, and the menstrual flow in combination group was more obvious than the other two groups. Conclusion: The combination of mifepristone and Guizhi Fuling decoction and the treatment of uterine fibroids is superior to that of monotherapy alone, and has clinical value of promotion.