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目的观察小梁切除术中结膜下注入Ｈｅａｌｏｎ ＧＶ对滤过泡的影响。方法急性闭角型青光眼 ３８例共５０眼，随机分为两组，Ａ组１７例（２５眼）为对照组，常规行角膜缘为基底的结膜瓣下的小梁切除术；Ｂ组１９例（２５眼），于角膜缘为基底的结膜瓣下的小梁切除术中之滤过部位结膜下注入Ｈｅａｌｏｎ ＧＶ ０．１～０． ２ｍｌ，术后观察滤过泡、前房、眼压、视力等情况，随访６个月，将滤过泡情况按ｋｒｏｎｆｅｄ标准分型登记，并统计手术成功率。结果 Ａ组 Ｉ型＋Ⅱ型滤过泡占 ６４％，而 Ｂ组占 ８８％。手术成功率 Ａ、Ｂ两组分别为 ７２％和 ９２％。术后 ４、５、 ６月两组眼压对比有显著性差异。结论Ｈｅａｌｏｎ ＧＶ球结膜下注射可增加滤过泡的成功率。
Objective To observe the effect of subconjunctival injection of Healon GV on filtration bleb during trabeculectomy. Methods A total of 50 eyes with acute angle-closure glaucoma were randomly divided into two groups. Group A (n = 17) (25 eyes) served as the control group. Conventional corneal limbal subconjunctival flap trabeculectomy was performed. In group B, 19 (25 eyes). Healon GV 0.1-0 was injected subconjunctivally at the filtering site in trabeculectomy under the limbus-based subconjunctival flap. 2ml, postoperative observation bleb, anterior chamber, intraocular pressure, visual acuity and so on, followed up for 6 months, the filtration bleb conditions according to the kronfed standard registration, and statistical success rate. Results Group A type II filter bleb 64%, while group B 88%. The success rate of surgery A and B were 72% and 92% respectively. There were significant differences in intraocular pressure between the two groups after 4,5 and 6 months. Conclusion Healon GV subconjunctival injection can increase the success rate of filtration bleb.