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目的对比分析不同剂量瑞芬太尼在无痛人工流产(人流)术中的应用效果。方法 138例进行无痛人流的女性患者,随机分成A、B、C组,每组46例。A、B、C组术中分别给予丙泊酚联合0.5、1.0、1.5μg/kg瑞芬太尼。观察三组麻醉效果。结果三组患者麻醉效果相比,差异均无统计学意义(P>0.05)。A组丙泊酚用量(1.59±0.64)mg/kg高于B组(1.28±0.75)mg/kg、C组(1.19±0.53)mg/kg,意识恢复时间(3.72±0.84)min、离院时间(22.44±2.47)min长于B组的(2.75±0.63)min和(19.02±2.15)min、C组的(2.64±0.71)min和(18.71±1.42)min,差异均有统计学意义(P<0.05)。结论在无痛人流术中选择1.0μg/kg瑞芬太尼联合丙泊酚效果明显,患者术后恢复快,可临床推广应用。
Objective To compare and analyze the effect of different doses of remifentanil in painless abortion (abortion). Methods 138 cases of painless female patients were randomly divided into A, B, C group, 46 cases in each group. Patients in groups A, B and C received propofol combined with remifentanil of 0.5, 1.0 and 1.5 μg / kg intraoperatively. Three groups observed anesthetic effect. Results There was no significant difference in anesthetic effect between the three groups (P> 0.05). In group A, the propofol dosage was (1.59 ± 0.64) mg / kg higher than that in group B (1.28 ± 0.75) mg / kg and in group C (1.19 ± 0.53) mg / kg and consciousness recovery time was 3.72 ± 0.84 (22.44 ± 2.47) min was significantly longer than that in group B (2.75 ± 0.63) min and (19.02 ± 2.15) min in group B and (2.64 ± 0.71) min and (18.71 ± 1.42) min in group C, respectively <0.05). Conclusion In the painless abortion in the choice of 1.0μg / kg remifentanil combined with propofol obvious effect in patients with fast recovery, can be clinically applied.