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本文旨在探索性激素与高血压病和冠心病发病关系,对中老年106例冠心病、122例高血压病人及174名健康者进行了睾酮(T)、雌二醇(E_2)、高密度脂蛋白胆固醇(HDL-C)的测定。试验结果表明:(1)正常人性激素水平与年龄相关;(2)二种疾病的男女患者T水平均显著低于健康者;(3)E_2水平男性明显高于正常人,女性则较正常人显著降低;(4)HDL-C和致动脉硬化指数(AI)值在正常人群中与年龄相关,而在二种疾病组与年龄不相关,同时还发现这二种疾病的HDL-C与健康人相比显著降低,而AI值明显增高。另外还发现这些变化与性激素的变化规律相关。作者认为E_2、T水平失调与这两种疾病的发病有关。
This article aims to explore the relationship between sex hormones and hypertension and coronary heart disease, coronary heart disease in 106 cases of middle-aged and elderly, 122 patients with hypertension and 174 healthy subjects were testosterone (T), estradiol (E 2), high-density lipids Determination of protein cholesterol (HDL-C). The results showed that: (1) the level of normal human sex hormones was related to age; (2) the T level of both men and women were significantly lower than that of healthy people; (3) The male of E_2 was significantly higher than that of normal (4) HDL-C and Arteriosclerosis Index (AI) values were age-related in normal population but not age in both groups, and HDL-C was also found to be associated with health Significantly lower in people, while the AI value was significantly higher. Also found that these changes and changes in sex hormones related. The authors believe that E 2, T level disorders and the incidence of these two diseases.