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高钙血症(TIH)是最常见的“癌旁综合征”之一,根据其原因,既往将肿瘤诱发的TIH分为局灶性溶骨性高钙血症及体液性高钙血症二大类,晚近研究发现,后者较前者更常见,在体液因素中最常见的是甲状旁腺激素相关性蛋白(PTHrP)。本文研究探讨肺癌时TIH与PTHrP的作用。 病例为1989～1994年收治的690例肺癌患者,男性501例,女性189例,平均年龄64(29～94)岁,腺癌379例,鳞癌207例,小细胞癌75例,大细胞癌29例。
Hypercalcemia (TIH) is one of the most common “cancer parasympathetic syndromes.” According to its causes, the previously induced tumor-induced TIH was classified into focal osteolytic hypercalcemia and humoral hypercalcemia. II. In the larger category, a recent study found that the latter is more common than the former, and parathyroid hormone-related protein (PTHrP) is most common in humoral factors. This study investigated the role of TIH and PTHrP in lung cancer. The cases were 690 lung cancer patients admitted from 1989 to 1994. There were 501 males and 189 females. The average age was 64 (29-94) years. There were 379 adenocarcinomas, 207 squamous cell carcinomas, 75 small cell carcinomas, and large cell carcinomas. 29 cases.