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目的探讨根除幽门螺旋杆菌(Helicobacter Pylori,HP)感染的最佳治疗方法;方法选择我院收治的86例HP阳性的消化性溃疡病例,随机分为A组和B组,A组采用左氧氟沙星+阿莫西林+奥美拉唑的联合用药方案;B组采用甲硝唑+阿莫西林+奥美拉唑的联合用药方案进行治疗,比较两组的治疗结果。结果A组HP根除率为86.0%(37/43),溃疡愈合率为79.1%(34/43),B组HP根除率为65.1%(28/43),溃疡愈合率为58.1%(25/43)。A组与B组相比两组之间差异具有统计学意义(P<0.05)。结论左氧氟沙星三联疗法根除HP感染的效果优于甲硝唑三联疗法。
Objective To investigate the best treatment for Helicobacter Pylori (HP) eradication. Methods Eighty-six cases of HP-positive peptic ulcer in our hospital were randomly divided into group A and group B. Group A was treated with levofloxacin + Moxillin + omeprazole combination regimen; B group with metronidazole + amoxicillin + omeprazole combination regimen for treatment, the treatment of the two groups were compared. Results The eradication rates of HP in group A were 86.0% (37/43), 79.1% (34/43) in group A, 65.1% (28/43) in group B, and 58.1% (25 / 43). The difference between group A and group B was statistically significant (P <0.05). Conclusion Levofloxacin triple therapy is superior to metronidazole triple therapy in eradicating HP infection.