目的　探讨 X刀治疗脑转移瘤的临床疗效及剂量规划。方法　用 X刀治疗 78例脑转移瘤 ,其中单发 46例 ,多发 32例。总病灶数 146个。覆盖剂量 2 2 Gy(2 0～ 2 5 Gy) ,周边剂量 18Gy(14～ 2 0 Gy) ,随访 3～ 2 4月。结果　临床症状 ,体征明显改善者 6 9例 (88.5 % ) ,无变化 7例 (9% ) ,加重 2例 (2 .5 % )。肿瘤控制率为 92 % ,平均生存期 11月。结论　 X刀治疗脑转移瘤临床疗效显著 ,可延长晚期肿瘤病人的生存期 ,减少恶性肿瘤的颅脑源性病死率 Objective To investigate the clinical efficacy and dose planning of X knife in the treatment of brain metastases. Methods X-knife treatment of 78 cases of brain metastases, including single in 46 cases, multiple in 32 cases. The total number of lesions 146. The coverage dose was 22 Gy (20 ~ 25 Gy) and the peripheral dose was 18 Gy (14 ~ 20 Gy), followed up for 3 ~ 2 months. Results Clinical symptoms and signs were significantly improved in 69 patients (88.5%), no changes in 7 patients (9%) and exacerbations in 2 patients (2.5%). The tumor control rate was 92% with an average survival of 11 months. Conclusion X knife treatment of brain metastases significant clinical effect, can extend the survival of patients with advanced cancer and reduce the incidence of craniocerebral malignant tumor mortality