人类免疫缺陷病毒(HIV)感染使全球面临严重问题,而对HIV新近感染的检测是估算HIV新发感染趋势研究的新方向。HIV核心蛋白p24抗原可早期检出因而用于HIV新近感染的检测,但因其敏感性低,对群体发病率的估计存在局限性;HIV核酸检测用于新近感染的判断敏感性和特异性都较高,尤其是集合核酸技术的应用降低了核酸检测技术本身的高成本;BED(指HIV-1特异的B、E和D亚型)捕获酶联免疫法的数据结果则更能反映出新近感染高危因素以及其他方面的变化规律,对评估HIV新发感染动态趋势起到积极作用。 Human immunodeficiency virus (HIV) infection is a serious problem worldwide, and the detection of recent HIV infection is a new direction for the study of trends in HIV infection. HIV core protein p24 antigen early detection and thus for the recent detection of HIV infection, but because of its low sensitivity to population estimates of the existence of limitations; HIV nucleic acid detection for the detection of recent infections sensitivity and specificity are The higher cost, especially the application of pooled nucleic acid technology, reduces the high cost of the nucleic acid detection technology itself; the data of the BED (which refers to HIV-1 specific subtypes B, E and D) Infection risk factors and other changes in the law, to assess the dynamic trend of new HIV infections play a positive role.