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30例口服降糖药物(OAD)血糖控制不佳的T2DM患者应用Glargine加用二甲双胍治疗3个月后,24小时血糖从15.7±2.8mmol/L降至7.1±1.3mmol/L,空腹血糖(FBG)从12.7±3.6mmol/L降至6.1±1.9mmol/L,餐后2小时血糖(PBG)从19.1±5.9mmol/L降至10.9±2.8mmol/L,HbAic从11.8±1.8mmol/L降至6.8±1.3mmol/L,低血糖从0增加至5次,来得时平均剂量为27.1±4.8μ/d,二甲双胍平均剂量为1500mg/d,患者体重指数无明显变化。
After 3 months of treatment with Glargine plus metformin, the blood glucose level decreased from 15.7 ± 2.8mmol / L to 7.1 ± 1.3mmol / L at 24 hours in 30 T2DM patients with poor glycemic control (OAD). The fasting blood glucose (FBG) ) Decreased from 12.7 ± 3.6mmol / L to 6.1 ± 1.9mmol / L, and the postprandial blood glucose (PBG) dropped from 19.1 ± 5.9mmol / L to 10.9 ± 2.8mmol / L at 2 hours. The HbAic decreased from 11.8 ± 1.8mmol / L To 6.8 ± 1.3mmol / L, hypoglycemia increased from 0 to 5, the average dose was 27.1 ± 4.8μ / d, the average dose of metformin was 1500mg / d, no significant change in the patient’s body mass index.