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目的了解住院分娩产妇乙型肝炎病毒表面抗原(HBsAg)携带状况,评价母亲HBsAg阳性的新生儿母婴阻断措施落实情况。方法对录入广西预防接种信息系统新生儿平台的2015-01-01/2016-06-30出生的个案和接种信息资料进行描述性分析。结果住院分娩产妇HBsAg阳性率为7.50%,市辖城区(5.77%)低于郊区(7.67%)和市辖县(7.74%),差异有统计学意义(χ~2=96.68,P=0.000);母亲HBsAg阳性的新生儿24h内乙肝疫苗(Hep B)接种率为96.91%,乙肝免疫球蛋白(HBIG)接种率为83.08%,HBIG+Hep B联合免疫接种率为82.49%,24h内总接种率(联合或单纯接种HBIG/Hep B)为97.51%;不同级别医院的产妇检测率(χ~2=3541.79,P=0.000)、24 h内联合免疫接种率(χ~2=148.80,P=0.000)和总接种率(χ~2=26.57,P=0.000)差异有统计学意义,其中市级医院的所有指标均为全市最高;2016年的联合免疫接种率(85.53%)高于2015年(80.90%)。未及时获得接种的主要原因是转儿科或转院(84人,占67.20%),其次为低体重或早产儿。结论农村地区产妇的HBsAg阳性率较高,农村地区所在的县、乡级接生医院的规范HBV母婴阻断率较低,应加强对基层接生医院产科人员的督导与培训。
Objective To understand the carrier status of hepatitis B virus surface antigen (HBsAg) in hospitalized delivery women and to evaluate the implementation of maternal and neonatal neonatal block strategy for HBsAg positive mothers. Methods A descriptive analysis of the cases and vaccination information collected from January 2015 to January 2016 on the Neonatal Platform of Guangxi Inoculation Information System was conducted. Results The positive rate of HBsAg in hospitalized women was 7.50%, lower in municipal districts (5.77%) than in suburbs (7.67%) and municipal districts (7.74%) (χ ~ 2 = 96.68, P = 0.000) ; Hep B vaccination rate was 96.91%, HBIG vaccination rate was 83.08%, HBIG + Hep B co-immunization rate was 82.49% within 24 hours of mothers HBsAg positive newborns, The rates of combined immunization (HBIG / Hep B) were 97.51%. The maternal detection rates (χ ~ 2 = 3541.79, P = 0.000) in different hospitals and the combined immunization rates 0.000), and total inoculation rate (χ ~ 2 = 26.57, P = 0.000). All the indexes in municipal hospitals were the highest in the city; the combined immunization rate in 2016 was 85.53%, higher than that in 2015 (80.90%). The main reason for the lack of timely immunization was pediatric or referral (84, accounting for 67.20%), followed by low birth weight or premature infants. Conclusions The HBsAg positive rate of maternal in rural areas is relatively high. The standard HBV maternal and infant block rate in county and township hospitals in rural areas is relatively low. Supervision and training of obstetric staff in primary birth clinics should be strengthened.